On this page you will find Dr. Lockwood’s selected publications, issued U.S. patents, and published patent applications.

For reprints of scientific articles, please contact Dr. Lockwood at sflockwood [at] baselodge.com.

Dr. Lockwood’s bio can be found here.

Selected Publications top

Issued U.S. Patents top

  • Lockwood, S. F., O’Malley, S., Watumull, D. G., Hix, L. M, Jackson, H., Nadolski, G. 2006-12-05. Structural carotenoid analogs for the inhibition and amelioration of disease. US 7,145,025. Assignee Hawaii Biotech Inc. Originally published Aug. 19, 2004.
  • Lockwood, S. F., Tang, P. C., Nadolski, G. T., Jackson, H. L., Fang, Z., Du, Y., Yang, M., Geiss, W. B., Williams, R., Burdick, D. C. 2007-07-24. Methods for the synthesis of astaxanthin. US 7,247,752. Assignee: Cardax Pharmaceuticals, Inc. Originally published Apr. 27, 2006.
  • Lockwood, S. F., O’Malley, S., Watumull, D. G., Hix, L. M., Jackson, H., Nadolski, G.  2008-01-08.  Carotenoid ester analogs or derivatives for the inhibition and amelioration of ischemic reperfusion injury.  US 7,317,008.  Assignee Cardax Pharmaceuticals, Inc.  Originally published Feb. 17, 2005.
  • Lockwood, S. F., O’Malley, S., Watumull, D. G., Hix, L. M., Jackson, H., Nadolski, G.  2008-01-22.  Pharmaceutical compositions including carotenoid ester analogs or derivatives for the inhibition and amelioration of disease.  US 7,320,997.  Assignee Cardax Pharmaceuticals, Inc.  Originally published Apr. 7, 2005.
  • Lockwood, S. F., O’Malley, S., Watumull, D. G., Hix, L., Jackson, H., Nadolski, G.  2008-03-18.  Carotenoid ether analogs or derivatives for the inhibition and amelioration of disease.  US 7,345,091.  Assignee Cardax Pharmaceuticals, Inc.  Originally published Jan. 13, 2005.
  • Lockwood, S. F., O’Malley, S., Watumull, D. G., Hix, L. M., Jackson, H., Nadolski, G.  2008-05-20.  Pharmaceutical compositions including carotenoid ether analogs or derivatives for the inhibition and amelioration of disease.  US 7,375,133.  Assignee Cardax Pharmaceuticals, Inc.  Originally published Mar. 24, 2005.
  • Lockwood, S. F., Tang, P. C., Nadolski, G., Jackson, H. L., Fang, Z., Du, Y., Yang, M., Geiss, W., Williams, R., Burdick, D.  2008-10-14.  Methods for synthesis of carotenoids, including analogs, derivatives, and synthetic and biological intermediates.  US 7,435,861.  Assignee Cardax Pharmaceuticals, Inc.  Originally published Dec. 28, 2006.
  • Lockwood, S. F., O’Malley, S., Watumull, D. G., Hix, L. M., Jackson, H., Nadolski, G.  2009-04-21.  Carotenoid analogs or derivatives for the inhibition and amelioration of disease.  US 7,521,584.  Assignee Cardax Pharmaceuticals, Inc.  Originally published May 26, 2005.
  • Lockwood, S. F., O’Malley, Watumull, D. G., Hix, L. M., Jackson, H., Nadolski, G.  2009-09-22.  Structural carotenoid analogs for the inhibition and amelioration of disease.  US 7,592,449.  Assignee Cardax Pharmaceuticals, Inc.  Originally published Oct. 12, 2006.
  • Lockwood, S. F., O’Malley, S., Jackson, H., Nadolski, G.  2010-04-06.  Carotenoid analogs or derivatives for the inhibition and amelioration of inflammation.  US 7,691,901.  Assignee Cardax Pharmaceuticals, Inc.  Originally published Nov. 24, 2005.
  • Lockwood, S. F., O’Malley, S., Watumull, D. G., Hix, L. M., Jackson, H., Nadolski, G.  2010-05-25.  Carotenoid ester analogs or derivatives for the inhibition and amelioration of liver disease.  US 7,723,327.  Assignee Cardax Pharmaceuticals, Inc.  Originally published Apr. 28, 2005.
  • Lockwood, S. F., O’Malley, S., Watumull, D. G., Hix, L. M., Jackson, H., Nadolski.  2010-07-27.  Carotenoid analogs or derivatives for controlling connexin 43 expression.  US 7,763,649.  Assignee Cardax Pharmaceuticals, Inc.  Originally published Jan. 13, 2005.

Published U.S. and World Patent Applications top

  • Lockwood, S. F., O’Malley, S., Watumull, D. G., Hix, L., Jackson, H. L., Nadolski, G. 2005. Carotenoid analogs or derivatives for the inhibition and amelioration of liver disease. US 2005/0004235. Assignee Hawaii Biotech Inc. Published Jan. 6, 2005.
  • Lockwood, S. F., O’Malley, S., Watumull, D. G., Hix, L., Jackson, H. L., Nadolski, G. 2005. Carotenoid ether analogs or derivatives for the inhibition and amelioration of disease. US 2005/0009758. Assignee Hawaii Biotech Inc. Published Jan. 13, 2005.
  • Lockwood, S. F., O’Malley, S., Watumull, D. G., Hix, L., Jackson, H. L., Nadolski, G. 2005. Carotenoid ester analogs or derivatives for controlling connexin 43 expression. US 2005/0009788. Assignee Hawaii Biotech Inc. Published Jan. 13, 2005.
  • Lockwood, S. F., O’Malley, S., Watumull, D. G., Hix, L., Jackson, H. L., Nadolski, G. 2005. Carotenoid analogs or derivatives for controlling connexin 43 expression. US 2005/0009930. Assignee Hawaii Biotech Inc. Published Jan. 13, 2005.
  • Lockwood, S. F., O’Malley, S., Watumull, D. G., Hix, L., Jackson, H. L., Nadolski, G. 2005. Carotenoid ether analogs or derivatives for the inhibition and amelioration of liver disease. US 2005/0026874. Assignee Hawaii Biotech Inc. Published Feb. 3, 2005.
  • Lockwood, S. F., O’Malley, S., Watumull, D. G., Hix, L., Jackson, H. L., Nadolski, G. 2005. Carotenoid ester analogs or derivatives for the inhibition and amelioration of ischemic reperfusion injury. US 2005/0037995. Assignee Hawaii Biotech Inc. Published Feb. 17, 2005.
  • Lockwood, S. F., O’Malley, S., Watumull, D. G., Hix, L., Jackson, H. L., Nadolski, G. 2005. Carotenoid ether analogs or derivatives for controlling C-reactive protein levels. US 2005/0049248. Assignee Hawaii Biotech Inc. Published Mar. 3, 2005.
  • Lockwood, S. F., O’Malley, S., Watumull, D. G., Hix, L., Jackson, H. L., Nadolski, G. 2005. Carotenoid ester analogs or derivatives for controlling C-reactive protein levels. US 2005/0059635. Assignee Hawaii Biotech Inc. Published Mar. 17, 2005.
  • Lockwood, S. F., O’Malley, S., Watumull, D. G., Hix, L., Jackson, H. L., Nadolski, G. 2005. Carotenoid analogs or derivatives for controlling C-reactive protein levels. US 2005/0059659. Assignee Hawaii Biotech Inc. Published Mar. 17, 2005.
  • Lockwood, S. F., O’Malley, S., Watumull, D. G., Hix, L., Jackson, H. L., Nadolski, G. 2005. Pharmaceutical compositions including carotenoid ether analogs or derivatives for the inhibition and amelioration of disease. US 2005/0065096. Assignee Hawaii Biotech Inc. Published Mar. 24, 2005.
  • Lockwood, S. F., O’Malley, S., Watumull, D. G., Hix, L., Jackson, H. L., Nadolski, G. 2005. Carotenoid ether analogs or derivatives for the inhibition and amelioration of ischemic reperfusion injury. US 2005/0065097. Assignee Hawaii Biotech Inc. Published Mar. 24, 2005.
  • Lockwood, S. F., O’Malley, S., Watumull, D. G., Hix, L., Jackson, H. L., Nadolski, G. 2005. Pharmaceutical compositions including carotenoid ester analogs or derivatives for the inhibition and amelioration of disease. US 2005/0075316. Assignee Hawaii Biotech Inc. Published Apr. 7, 2005.
  • Lockwood, S. F., O’Malley, S., Watumull, D. G., Hix, L., Jackson, H. L., Nadolski, G. 2005. Pharmaceutical compositions including carotenoid analogs or derivatives for the inhibition and amelioration of disease. US 2005/0075337. Assignee Hawaii Biotech Inc. Published Apr. 7, 2005.
  • Lockwood, S. F., O’Malley, S., Watumull, D. G., Hix, L., Jackson, H. L., Nadolski, G. 2005. Carotenoid ester analogs or derivatives for the inhibition and amelioration of liver disease. US 2005/0090469. Assignee Hawaii Biotech Inc. Published Apr. 28, 2005.
  • Lockwood, S. F., O’Malley, S., Watumull, D. G., Hix, L., Jackson, H. L., Nadolski, G. 2005. Carotenoid analogs or derivatives for the inhibition and amelioration of disease. US 2005/0113372. Hawaii Biotech Inc. Published May 26, 2005.
  • Lockwood, S. F., O’Malley, S., Watumull, D. G., Hix, L., Jackson, H. L., Nadolski, G. 2005. Carotenoid analogs or derivatives for the inhibition and amelioration of ischemic reperfusion injury. US 2005/0143475. Assignee Hawaii Biotech Inc. Published Jun. 30, 2005.
  • Lockwood, S. F., O’Malley, S., Watumull, D. G., Hix, L., Jackson, H. L., Nadolski, G. 2005. Carotenoid ether analogs or derivatives for controlling connexin 43 expression. US 2005/0148517. Assignee Hawaii Biotech Inc. Published Jul. 7, 2005.
  • Lockwood, S. F., O’Malley, S., Jackson, H. L., Nadolski, G. 2005. Carotenoid analogs or derivatives for the inhibition and amelioration of inflammation. US 2005/0261254. Assignee Hawaii Biotech Inc. Published Nov. 24, 2005.
  • Lockwood, S. F., O’Malley, S., Jackson, H. L., Nadolski, G. 2006. Carotenoid analogs or derivatives for the inhibition and amelioration of inflammation. US 2006/0058269. Assignee Hawaii Biotech Inc. Published Mar. 16, 2006.
  • Lockwood, S. F., Tang, P. C., Nadolski, G. T., Jackson, H. L., Fang, Z., Du, Y., Yang, M., Geiss, W. B., Williams, R., Burdick, D. C. 2006. Methods for the synthesis of zeazanthin. US 2006/0088905. Assignee Hawaii Biotech Inc. Published Apr. 27, 2006.
  • Lockwood, S. F., Tang, P. C., Nadolski, G. T., Jackson, H. L., Fang, Z., Du, Y., Yang, M., Geiss, W. B., Williams, R., Burdick, D. C. 2006. Methods for the synthesis of chiral dihydroxy ketone intermediates useful for the chiral synthesis of carotenoids. US 2006/0111580. Assignee Hawaii Biotech Inc. Published May 25, 2006.
  • Lockwood, S. F., Tang, P. C., Nadolski, G., Jackson, H. L., Fang, Z., Du, Y., Yang, M., Geiss, W., Williams, R., Burdick, D. 2006. Methods for the synthesis of lutein. US 2006/155150. Assignee Hawaii Biotech Inc. Published Jul. 13, 2006.
  • Lockwood, S. F., Tang, P. C., Nadolski, G., Jackson, H. L., Fang, Z., Du, Y., Yang, M., Geiss, W., Williams, R., Burdick, D. 2006. Methods for the synthesis of unsaturated ketone intermediates useful for the synthesis of carotenoids. US 2006/167319. Assignee Hawaii Biotech Inc. Published Jul. 27, 2006.
  • Lockwood, S. F., Tang, P. C., Nadolski, G., Jackson, H. L., Fang, Z., Du, Y., Yang, M., Geiss, W., Williams, R., Burdick, D. 2006. Methods for the synthesis of chiral dihydroxy intermediates useful for the chiral synthesis of carotenoids. US 2006/178538. Assignee Hawaii Biotech Inc. Published Aug. 10, 2006.
  • Lockwood, S. F., Tang, P. C., Nadolski, G., Jackson, H. L., Fang, Z., Du, Y., Yang, M., Geiss, W., Williams, R., Burdick, D. 2005. Methods for the synthesis of astaxanthin. US 2006/183185. Assignee Hawaii Biotech Inc. Published Aug. 17, 2006.
  • Lockwood, S. F., Tang, P. C., Nadolski, G., Jackson, H. L., Fang, Z., Du, Y., Yang, M., Geiss, W., Williams, R., Burdick, D. 2006. Methods for the synthesis of astaxanthin. US 2006/183947. Assignee Hawaii Biotech Inc. Published Aug. 17, 2006.
  • Lockwood, S. F., O’Malley, S., Watumull, D. G., Hix, L. M., Jackson, H., Nadolski, G. 2006. Structural carotenoid analogs for the inhibition and amelioration of disease. US 2006/229446. Assignee Hawaii Biotech Inc. Published Oct. 12, 2006.
  • Lockwood, S. F., Nadolski, G. 2006. Carotenoids, carotenoid analogs, or carotenoid derivatives for the treatment of visual disabilities. US 2006/270589. Assignee Hawaii Biotech, Inc. Published Nov. 30, 2006.
  • Lockwood, S. F., Nadolski, G. 2006. Reduction in complement activation and inflammation during tissue injury by carotenoids, carotenoid analogs, or derivatives thereof. US 2006/270590. Assignee Hawaii Biotech, Inc. Published Nov. 30, 2006.
  • Lockwood, S. F., Nadolski, G., Frey, D. A., McLaws, M., King, T. J., Burdick, D. 2006. Carotenoids, carotenoid analogs, or carotenoid derivatives for the treatment of proliferative disorders. US 2006/276372. Assignee Hawaii Biotech, Inc. Published Dec. 7, 2006.
  • Lockwood, S. F., Tang, P. C., Nadolski, G., Jackson, H. L., Fang, Z., Du, Y., Yang, M., Geiss, W., Williams, R., Burdick, D. 2006. Methods for synthesis of carotenoids, including analogs, derivatives, and synthetic and biological intermediates. US 2006/293545. Assignee Hawaii Biotech, Inc. Published Dec. 28, 2006.
  • Lockwood, S. F., Nadolski, G. 2006. Water-dispersible carotenoids, including analogs and derivatives. US 2007/15735. Assignee Hawaii Biotech, Inc. Published Jan. 18, 2007.
  • Lockwood, S. F.  2007.  Structural carotenoid analogs or derivatives for the modulation of systemic and/or target organ redox status.  US 2007/0238793.  Assignee Hawaii Biotech, Inc.  Published Oct. 11, 2007.
  • Lockwood, S. F., Tang, P. C., Nadolski, G., Jackson, H. L., Fang, Z., Du, Y., Yang, M., Geiss, W., Williams, R., Burdick, D., Braun, C.  2008.  Methods for synthesis of carotenoids, including analogs, derivatives, and synthetic and biological intermediates.  US 2008/0221377.  Assignee Cardax Pharmacetuicals, Inc.  Published Sep. 11, 2008.
  • Lockwood, S. F., Mason, R. P.  2008.  Use of carotenoids and/or carotenoid derivatives/analogs for reduction/inhibition of certain negative effects of COX inhibitors.  US 2008/0293679.  Assignee Cardax Pharmaceuticals, Inc.  Published Nov. 27, 2008.
  • Foss, B. J., Nadolski, G. T., Lockwood, S. F.  2009.  Synthesis of carotenoid analogs or derivatives with improved antioxidant characteristics.  US 2009/0099061.  Assignee Cardax Pharmaceuticals, Inc.  Published Apr. 16, 2009.
  • Lockwood, S. F., Mason, R. P.  2009.  Carotenoid analogs and derivatives for the prevention of platelet aggregation.  US 2009/0124574.  Assignee Cardax Pharmaceuticals, Inc.  Published May 14, 2009.
  • Lockwood, S. F., O’Malley, S., Watumull, D. G., Hix, L. M., Jackson, H., Nadolski, G.  Canadien Patent Application CPA 2,495,167.  Analogues de carotenoides structuraux pour l’inhibition et la reduction de maladie.  Assignee Hawaii Biotech, Inc.  PCT publication date Feb. 5, 2004.
  • Lockwood, S. F., O’Malley, S., Watumull, D. G., Hix, L. M., Jackson, H., Nadolski, G.  European Patent Office EP 1,532,108.  Structural carotenoid analogs for the inhibition and amelioration of disease.  Assignee Hawaii Biotech, Inc.  EP publication date May 25, 2005.
  • Lockwood, S. F., O’Malley, S., Watumull, D. G., Hix, L. M., Jackson, H., Nadolski, G.  Patent Cooperation Treaty WO 2004/011423.  Structural carotenoid analogs for the inhibition and amelioration of disease.  Assignee Hawaii Biotech, Inc.  WO publication date Feb. 5, 2004.
  • Lockwood, S. F., O’Malley, S., Jackson, H., Nadolski, G.  Patent Cooperation Treaty WO 2005/102356.  Carotenoid analogs or derivatives for the inhibition and amelioration of inflammation.  Assignee Hawaii Biotech, Inc.  WO publication date Nov. 3, 2005.
  • Lockwood, S. F., Tang, P. C., Nadolski, G., Fang, Z., Du, Y., Geiss, W., Williams, R., Burdick, D.  Patent Cooperation Treaty WO 2006/039685.  Methods for synthesis of chiral intermediates of carotenoids, carotenoid analogs, and carotenoid derivatives.  Assignee Hawaii Biotech, Inc.  WO publication date Apr. 13, 2006.

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